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Bio

 

 

 

  2016.05-     Associate Professor, School of Life Sciences, Lanzhou University

 

2011.07-2016.04  Lecturer, School of Life Sciences, Lanzhou University

 

 

 
Academic Appointments

2005.09-2011.07 Ph.D., School of Life Sciences, Lanzhou University, Lanzhou, China

2008.09-2010.07 Joint Training of Ph.D. students in State-sponsored Postgraduate Program for Building High-level Universities, University of Maryland, College Park, USA

2001.09-2005.07  B.S., School of Life Sciences, Henan Normal University, Xinxiang, China

Administrative Appointments

Honors & Awards

Funding

1. The roles of ROS and ATM in the regulation of spermidine-induced mitophagy. National Natural Science Foundation of China, 31300941, 2014.01-2016.12.

           2. The effect and mechanism of Lead-induced mitophagy in mouse model. Natural Science Foundation of Gansu Province, 145RJZA120, 2014.01-2016.12.

   3. The molecular mechanism of nutritional regulation in DNA damage response, cancer prevention and aging. Natural Science Foundation of Gansu Province, 1010RJZA107, 2010.01-2012.12.

   4. The signaling pathway of Lead-induced mitophagy in HEK293 cells. Fundamental Research Funds for the Central Universities, lzujbky-2014-91, 2014.01-2015.12

Publications

 # First author; * Corresponding author.

1.Sajid Naeem, Yongmei Qi*, Yihong Tian, Yingmei Zhang*. NIX compensates lost role of Parkin in Cd-induced mitophagy in HeLa cells. Toxicology Letters, 2020, In press. 

2. Chen Zhang, Dong Li, Tingting Ge, Jiangyuan Han, Yongmei Qi*, Dejun Huang*. 2,4-Dichlorophenol induces feminization of zebrafish (Danio rerio) via DNA methylation. Science of the Total Environment. 2020, 708:135084.

3.Cong Yuan, Chen Zhang, Yongmei Qi, Dong Li, Yan Hu, Dejun Huang*, 2.2,4-Dichlorophenol induced feminization of zebrafish by down-regulating male-related genes through DNA methylation. Ecotoxicology and Environmental Safety. 2019 Dec 6;189:110042. doi: 10.1016/j.ecoenv.2019.110042 

4. Xueyan Gu, Yongmei Qi*,Zengxiu Feng,Lin Ma, Ke Gao,Yingmei Zhang*, Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Toxicology Letters, 2018, 291:92-100. 

5. Yongmei Qi#, Qian Qiu#, Xueyan Gu, Yihong Tian, Yingmei Zhang*, ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts, Scientific Reports, 2016, 6, 24700. 

6. Yongmei Qi, Yingmei Zhang*, Yingxia Liu, Wenya Zhang, Nonylphenol decreases viability and arrests cell cycle via reactive oxygen species in Raji cells, Experimental and Toxicologic Pathology, 2013, 65 (1-2): 69-72.

7. Yongmei Qi, Ailing Li, Dejun Huang, Yihong Tian, Yingmei Zhang*, Exogenous S-adenosyl-L-methionine could inhibit c-myc overexpression induced by As2O3 in normal human liver HL-7702 cells, Journal of Health Science, 2011, 57(2): 188-191.

8. Yongmei Qi, Norberta W Schoene, Frederick M Lartey, Wen-Hsing Cheng*, Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells, The Journal of Biological Chemistry, 2010, 285(43): 33010–33017.

9. Dejun Huang*, Xiaoning Zhang, Chen Zhang, Hui Li, Dong Li, Yan Hu, Feng Yang, Yongmei Qi. 2018. 2,4-Dichlorophenol induces DNA damage through ROS accumulation and GSH depletion in goldfish Carassius auratus. Environ Mol Mutagen. 59, 798-804. 

10. Tingting Ge, Jiangyuan Han, Yongmei Qi, Xueyan Gu, Lin Ma, Chen Zhang, Sajid Naeem, Dejun Huang*. 2017. The toxic effects of chlorophenols and associated mechanisms in fish. Aquatic Toxicology. 184, 78-93. 

11. Xue Wei, Yongmei Qi, Xiaoning Zhang, Xueyan Gu, Hui Cai, Jing Yang, Yingmei Zhang*, ROS act as an upstream signal to mediate cadmium-induced mitophagy in mouse brain, Neurotoxicology, 2015, 46:19-24.

12. Xue Wei, Yongmei Qi, Xiaoning Zhang, Qian Qiu, Xueyan Gu, Chen Tao, Dejun Huang, Yingmei Zhang*, Cadmium induces mitophagy through ROS-mediated PINK1/Parkin pathway, Toxicology Mechanisms and Methods, 2014, 24(7):504-511.

13. Zhen An, Yongmei Qi, Dejun Huang, Xueyan Gu, Yihong Tian, Ping Li, Hui Li, Yingmei Zhang*, EGCG inhibits Cd2+-induced apoptosis through scavenging ROS rather than chelating Cd2+ in HL-7702 cells, Toxicology Mechanisms and Methods, 2014, 24(4): 259-267.

14. Xiaoning Zhang, Xiaona Zhang, Yongmei Qi, Dejun Huang*, Yingmei Zhang*,  2,4-Dichlorophenol induces ER stress-mediated apoptosis via eIF2a dephosphorylation in vitroEnvironmental Toxicology, 2016, 31(2): 245-255.

15. Weiwei Li, Xueyan Gu, Xiaoning Zhang, Jinxin Kong, Nan Ding, Yongmei Qi, Yingmei Zhang, Jufang Wang, Dejun Huang*, Cadmium delays non-homologous end joining (NHEJ) repair viainhibition of DNA-PKcs phosphorylation and downregulation ofXRCC4 and Ligase IV, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2015, 779: 112-123. 

16. Xiaoning Zhang, Xiaona Zhang, Zhidan Niu, Yongmei Qi, Dejun Huang*, Yingmei Zhang*, 2,4,6-Trichlorophenol cytotoxicity involves oxidative stress, endoplasmic reticulum stress and apoptosis, International Journal of Toxicology, 2014, 33(6): 532-541.

17. Xiaoning Zhang, Hui Li, Qian Qiu, Yongmei Qi, Dejun Huang*, Yingmei Zhang*, 2,4-Dichlorophenol induces global DNA hypermethylation through the increase of S-adenosylmethionine and the upregulation of DNMTs mRNA in the liver of goldfish Carassius auratusComparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology, 2013, 160C: 54-59.

18. Hui Li, Xiaoning Zhang, Qian Qiu, Zhen An, Yongmei Qi, Dejun Huang*, Yingmei Zhang*, 2,4-dichlorophenol induces apoptosis in primary hepatocytes of grass carp (Ctenopharyngodon idella) through mitochondrial pathway, Aquatic Toxicology, 2013, 140-141: 117-122.

19. Peng Chen, Yingxia Liu, Yanqing Sun, Che Chen, Yongmei Qi, Yingmei Zhang*, AZT and emodin exhibit synergistic growth-inhibitory effects on K562/ADM cells by inducing S phase cell cycle arrest and suppressing MDR1 mRNA/p-gp protein expression, Pharmacology Biology, 2013, 51(12):1586-1591.

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