兰州大学生命科学学院 教授 李祥锴

学习经历

1997-2001: 武汉大学生命科学学院微生物专业,学士

1997-2001: Wuhan University, School of life science, Microbiology major, Bachelor

2001-2008: 美国俄克拉荷玛大学植物与微生物系,微生物专业,硕士、博士

2001-2008: University of Oklahoma, School of plants and microbiology, Microbiogy major, USA, MA & PhD

工作经历

2008-2010:美国贝勒医学院儿童营养学院,博士后

2008-2010: Baylor college of medicine, Institute of child nutrition, USA, post-doctor

2010- 至今:  兰州大学生命科学学院,微生物研究所,教授,博导

2010 till now: Lanzhou University, School of Life science, Institute of microbiogy, Professor, doctor surpervisor

 

教学及指导研究生情况

硕士研究生招生方向 :微生物研究所环境微生物方向。

录取要求:对环境微生物学研究感兴趣,英语通过四级。

优先考虑:发表过科学论文(排名不限);英语通过六级;从事过学生工作。

毕业要求:以第一作者发表SCI论文一篇(不限影响因子,分区)。

Master Recruition Orientation: Insititute of microbiology, Environmental microbiogy orientation

Admission Requirement: Interested in enviromental microbiology research, Passing CET-4

Top-priority: Paper published(regardness of ranking); Passing CET-6, engaged in student work before

Graduation requirement: Pubilishing one SCI paper as first author(regardness of IF and partition)

博士研究生招生方向 :微生物研究所环境微生物方向。

录取要求:对环境微生物学研究感兴趣,英语通过四级。

优先考虑:发表过科学论文(排名不限);英语通过六级;从事过学生工作。

毕业要求:以第一作者发表SCI论文两篇(不限影响因子,分区)。

Doctor Recruition Orientation: Insititute of microbiology, Environmental microbiogy orientation

Admission Requirement: Interested in enviromental microbiology research, Passing CET-4

Top-priority: Paper published(regardness of ranking); Passing CET-6, engaged in student work before

Graduation requirement: Pubilishing two SCI papers as first author(regardness of IF and partition)

主讲课程:
秋季学期: 研究生高级英文论文写作,兰州大学硕士、博士研究生公选课程,生命科学学院硕士、博士研究生必修课程;高级英文论文写作,萃英学院本科必修课程;兰大导读,生命科学学院本科必修课程

春季学期:生物信息学应用初步,生命科学学院硕士、博士研究生必修课程

Main courses:

Fall semister: Advanced English writing of postgraduate, Public elective course and required course for postgraduates in School of biology, Lanzhou university; Advanced English writing, Required course for undergraduates of Cuiying Institute; Guided reading, Required course for undergraduates of School of biology 

Spring semister: Primary application of bioinformatics, Required course for postgraduates in School of biology

 

发表论文及专著
近期发表部分论文:(*,通讯作者)
  • Chen, Y., Tian, X. Z., Bai, L., Liu, Z. Q., Xiao, X. P., Liu, P., & Li, X. K*. (2017). Effects of human opiorphin on food intake and water intake in mice following central administration. Neuroscience letters, 641, 62-69.(IF=2.11)

  • Chen, Z., Niu, Y., Zhao, S., Khan, A., Ling, Z., Chen, Y., Liu, P., Li, X., 2016. A novel biosensor for p-nitrophenol based on an aerobic anode microbial fuel cell. Biosensors and Bioelectronics, 85, 860-868.(IF=7.46)

  • Huang, H., Wu, K., Khan, A., Jiang, Y., Ling, Z., Liu, P., Chen, Y., Tao, X., Li, X*. 2016. A novel Pseudomonas gessardii strain LZ-E simultaneously degrades naphthalene and reduces hexavalent chromium. Bioresource technology, 207, 370-378(IF=4.92)

  • Yu, X., Jiang, Y., Huang, H., Shi, J., Wu, K., Zhang, P., ... & Li, X*. (2016). Simultaneous aerobic denitrification and Cr (VI) reduction by Pseudomonas brassicacearum LZ-4 in wastewater. Bioresource Technology, 221, 121-129. (IF=4.92)

  • Yu, Z., He, Z., Tao, X., Zhou, J., Yang, Y., Zhao, M., ... & Li X.*(2016). The shifts of sediment microbial community phylogenetic and functional structures during chromium (VI) reduction. Ecotoxicology, 25(10), 1759-1770.(IF=2.33)

  • Wenyang Wu, Haiying Huang, Zhenmin Ling, Zhengsheng Yu, Yiming Jiang, Pu Liu, Xiangkai Li§. Genome sequencing reveals mechanisms for heavy metal resistance and polycyclic aromatic hydrocarbon degradation in Delftia lacustris strain LZ-C. Ecotoxicology. 2016, 25(1): 234-247. (IF=2.33)

  • Yuan, W., Yang, N., & Li, X*. (2016). Advances in Understanding How Heavy Metal Pollution Triggers Gastric Cancer. BioMed Research International, 2016.(IF=2.13)

  • Zhang, H., Ma, Y., Liu, P., & Li, X*. (2016). Multidrug resistance operon emrAB contributes for chromate and ampicillin co-resistance in a Staphylococcus strain isolated from refinery polluted river bank. SpringerPlus, 5(1), 1648.(IF=0.98)

  • Zhe Zheng, Yabo Li , Xiaowei Zhang , Pu Liu , Jun Ren , Gaofeng Wu , Yanli Zhang , Yong Chen , Xiangkai Li*(2015).A Bacillus subtilis strain can reduce hexavalent chromium to trivalent and an nfrA gene is involved[J]. International Biodeterioration & Biodegradation, 2015, 97: 90-96.(IF=2.43)

  • Han, S., Zhang, H., Xie, Y., Liu, L., Shan, C., Li, X., ... & Tang, Y. (2015). Application of cow milk-derived carbon dots/Ag NPs composite as the antibacterial agent. Applied Surface Science, 328, 368-373.

  • Liu, X., Wu, G., Zhang, Y., Wu, D., Li, X., & Liu, P. (2015). Chromate Reductase YieF from Escherichia coli Enhances Hexavalent Chromium Resistance of Human HepG2 Cells. International Journal of Molecular Sciences, 16(6), 11892-11902.

  • Jiang, Y., Huang, H., Wu, M., Yu, X., Chen, Y., Liu, P., & Li, X*. (2015). Pseudomonas sp. LZ-Q continuously degrades phenanthrene under hypersaline and hyperalkaline condition in a membrane bioreactor system. Biophysics Reports, 1(3), 156-167.

  • Chen, Z., Zou, L., Zhang, H., Chen, Y., Liu, P., & Li, X.* (2014). Thioredoxin is involved in hexavalent chromium reduction in Streptomyces violaceoruber strain LZ-26-1 isolated from the Lanzhou reaches of the Yellow River.International Biodeterioration & Biodegradation, 94, 146-151.(IF=2.43)

  • Shigaki, T., & Li, X.* (2014). Editorial: Special Issue: Genetically Modified Foods: Are they Really Better?). Recent patents on food, nutrition & agriculture, 6(1), 2.

  • Han, S., Zhang, H., Zhang, J., Xie, Y., Liu, L., Wang, H., Li, X.,... & Tang, Y. (2014). Fabrication, gradient extraction and surface polarity-dependent photoluminescence of cow milk-derived carbon dots. RSC Advances, 4(101), 58084-58089.

  • Yao, Y., Luo, Y., Yang, Y., Sheng, H., Li, X., Li, T., ... & An, L. (2014). Water free anaerobic co-digestion of vegetable processing waste with cattle slurry for methane production at high total solid content. Energy74, 309-313.

  • Yao, Y., Sheng, H., Luo, Y., He, M., Li, X., Zhang, H., ... & An, L. (2014). Optimization of anaerobic co-digestion of Solidago canadensis L. biomass and cattle slurry. Energy78, 122-127.

  • Zou, L., Chen, Z., Zhang, X., Liu, P., & Li, X.* (2014). Phosphate promotes uranium (VI) adsorption in Staphylococcus aureus LZ‐01. Letters in applied microbiology.(IF=1.58)

  • Zhang, X., Wu, W., Virgo, N., Zou, L., Liu, P., & Li, X.* (2014). Global transcriptome analysis of hexavalent chromium stress responses in Staphylococcus aureus LZ-01. Ecotoxicology, 1-12.(IF=2.33)

  • Chen, Z., Zou, L., Zhang, H., Chen, Y., Liu, P., & Li, X.* (2014). Thioredoxin is involved in hexavalent chromium reduction in< i> Streptomyces violaceoruber strain LZ-26-1 isolated from the Lanzhou reaches of the Yellow River. International Biodeterioration & Biodegradation, 94, 146-151.

  • Li, X., Zhang, H., Ma, Y., Liu, P., Krumholz, L. R.,Genes required for alleviation of uranium toxicity in sulfate reducing bacterium Desulfovibio alaskensis G20.Ecotoxicology, 1-8,2014.(IF=2.33)

  • Wu, G., Sun, M., Liu, P., Zhang, X., Yu, Z., Zheng, Z., Chen, Y., Li, X.*Enterococcus faecalis strain LZ‐11 isolated from Lanzhou reach of the Yellow River is able to resist and absorb Cadmium. Journal of applied microbiology,DOI: 10.1111/jam.12460,2014. (注:第一作者之一发表该文为大四)(IF=2.16)

  • Yu, Z., Li, J., Li, Y., Wang, Q., Zhang, X., Wu, G., Liu, P., Li, X*. A mer operon confers mercury reduction in a Staphylococcus epidermidis strain isolated from Lanzhou reach of the Yellow River. International Biodeterioration & Biodegradation,Accepted. ,2014 .(注:第一作者之一发表该文为大四)(IF=2.43)

  • Tao X, Yan L, Yu Z, Zhao M, Zhang X, Li X* (2013) Structural and Functional Characterization of a Soil Microbial Community which is Able to Convert Waste Cooking Oil to Fatty-acid-Derived Fuels. J Bioremed Biodeg 4: 201. doi:10.4172/2155-6199.1000201 (注:共同第一作者发表该文分别为研一、大四)(IF=1.23)

  • Luming Zou,Pu Liu ,Xiangkai Li* (2013) New advances molecular mechanism of microbial hexavalent chromium reduction. International Journal of Biotechnology and Food Science,Vol. 1(2) (Invited Review)

  • Zhang X, Krumholz LR, Yu Z, Chen Y, Liu P, Li X* (2013) A Novel Subspecies of Staphylococcus aureus from Sediments of Lanzhou Reach of the Yellow River Aerobically Reduces Hexavalent Chromium. J Bioremed Biodeg 4:188. doi:10.4172/2155-6199.1000188  (注:第一作者发表该文为研一)

  • Xuanyu Tao, Yabo Li, Haiying Huang, Yong Chen, Pu Liu, Xiangkai Li* (2013) Desulfovibrio vulgaris Hildenborough prefers lactate over hydrogen as electron donor. Annals of Microbiology  (注:第一作者之一发表该文为研一)

  • 闫莉,陶玄宇,吴文波,迟亮,孙梅,张笑薇,于政升,李祥锴*(2013)可将地沟油降解为生物柴油的微生物群落结构和功能研究,中国论文在线(注:论文评级四星,第一作者发表该文为大四)

  • Li X*, Yang J, Manary M, Hirschi KD (2012) Biotechnologically-Modified Cassava: Protein Absorption Relative to Casein. J Bioequiv Availab 4: 040-043. doi:10.4172/jbb.1000109

  • Li X*, Yang J, Morris J, Hester A, Nakata PA, Hirschi KD, Genetically Modified Medicago truncatula Lacking Calcium Oxalate has Increased Calcium Bioavailability and Partially Rescues Vitamin D Receptor Knockout Mice Phenotypes. J Bioequiv Availab 5: 047-052. doi:10.4172/jbb.1000133

  • 邹路明,李祥锴*(2013)转基因的草酸钙缺失蒺藜苜蓿的钙生物可利用率增加并能部分恢复维生素D受体缺失小鼠的表型,J Bioequiv Availab (中文版)

  • Li X, Krumholz LR, Thioredoxin is involved in U(VI) and Cr(VI) reduction in Desulfovibrio desulfuricans G20, Journal of bacteriology;191(15):4924-33;2009

  • Li X, Krumholz LR, Regulation of arsenate resistance in Desulfovibrio desulfuricans G20 by an arsRBCC operon and an arsC gene, Journal of Bacteriology, May 2007, p. 3705-3711, Vol. 189, No. 10.

专利:

1. 一种工业污染物浓度检测装置,李祥锴;张骁;王绪国;武奇, 2015、/1/5,中国,中华人民共和国国家知识产权局,201520892128.3

2. 一种基于微生物燃料电池的对硝基苯酚浓度检测系统和方法,李祥锴;张骁;陈正军;王绪国;邵天一;武奇,2015/8/26, 中国, ( 中国人民共和国国家知识产权局),201510531866.X.

3. 利用Pseudomonas fluorescens菌株LZ-4修复六价铬和萘复合污染环境的方法,2015/2/6, 中国, 中华人民共和国国家知识产权, 201510064744.4.

4. 一种简易膜生物反应器,李祥锴、姜一鸣、黄海鹰、王啟辉、余萱、罗泽华,2015/7/22, 中国, 中华人民共和国国家知识产权, 201520534762X

5. 一种简易膜生物反应器及使用方法,李祥锴、姜一鸣、黄海鹰、王啟辉、余萱、罗泽华,2015/7/22, 中国, 中华人民共和国国家知识产权, 2015104358299

6. 一种新型生态鱼缸,李祥锴、姜一鸣、黄海鹰、王啟辉、罗泽华、姜希毅、黄海凌,2015/7/22, 中国, 中华人民共和国国家知识产权, 2015205713518

 

研究方向

1.黄河兰州段受污染微生物群落结构功能与周边环境的相互作用

2.黄河兰州段受污染特色微生物的分离及功能分子机理鉴定与应用前景探究

3.微生物燃料电池与膜生物反应器耦合处理废水

4.我国西部地区及一带一路区域物质能源的开发与利用

主要合作实验室来自:1.美国俄克拉玛大学 2.意大利卡拉布里亚大学 3.清华大学 4. 武汉大学 5. 中国科学院南京地理与湖泊研究所 6.甘肃省膜科学研究院

  1. The Interaction between community structure and function of microbial organism and surrounding polluted enviroment in the Yelllow River of Lanzhou reach
  2. Research on the isolation, molecular mechanism and application perspective of specific microbioly organisms reisitant to polluted enviroment in the Yelllow River of Lanzhou reach
  3. Coupling Microbial fuel cell and Membrane bioreactor to wastewater discharge
  4. Exploration and application of biomass energy of western area and “One Belt and One Road”area

Main cooperation Lab: 1.University of Oklahoma,USA 2.University of Calabria, Italy 3.TsingHua University 4.WuHan University 5. Nanjing instotute of geography and limnology,Chinese acedemic of sciences 6.Institute of membrane science in Gansu province

项目成果

2011年至今,以项目负责人身份获得科技部国际合作项目一项、国际培训项目一项,国家自然科学基金委青年项目一项、面上项目一项、甘肃省科技厅国际合作项目一项、教育部留学回国基金一项以及横向合作项目一项,总经费超过1000万元

From year 2011  till now, As project leader got one ministry of science and techonology project of international cooperation, one international training program, one national natural science foundation youth project, one general program, one department of international cooperation project in Gansu province, one ministry of educational returned funds and one crossing research project, total funding were more than 700 million.

荣誉、获奖
  • 韩华雯,李祥锴*,copper(II)coordination of NfoR protein stimulates its Cr(VI) reduction ability, 中国环境微生物2016年年会,评为会议优秀论文,第一作者获得该年度简浩然奖学金
  • 指导兰州大学代表队参加美国波士顿2016年国际遗传机器设计大赛总决赛,参赛项目“Reduced bioaccumulated heavy metals in fish by gut remediation”获得大赛银奖
  • 指导兰州大学代表队参加美国波士顿2015年国际遗传机器设计大赛总决赛,参赛项目“Micro Holmes(小福尔摩斯)”获得大赛银奖
  • 指导兰州大学代表队参加美国波士顿2014年国际遗传机器设计大赛总决赛,参赛项目“利用微生物燃料电池测量对硝基苯浓度”获得大赛银奖
  • 陈勇, 李祥锴*, 硫还原细菌G20还原铬的分子机理,中国环境微生物2010年年会,评为会议优秀论文,第一作者获得该年度简浩然奖学金
  • 张笑薇, 李祥锴*, 黄河兰州段分离可还原六价铬金黄色葡萄球菌的功能鉴定,中国环境微生物2012年年会,评为会议优秀论文,第一作者获得该年度简浩然奖学金(时为研一)
  • 陶玄宇,李祥锴*, 一株假单胞菌同时降解萘与还原六价铬的机理研究,中国环境微生物2014年年会,评为会议优秀论文,第一作者获得该年度简浩然奖学金(时为研二)
  • 2012年指导学生完成国家创新项目“Staphylococcus aureus LZ-01中与Cr(Ⅵ)还原相关基因的筛选与鉴定”获得甘肃省挑战杯一等奖,并代表兰州大学参加全国挑战杯大赛
  • 2012年获兰州大学本科生创新创业项目优秀指导老师
  • Corresponding author of Jian, Haoran Honor Scholar Rewards 2016
  • Silver medalist of International Genetic Engineered Machine Contest 2016
  • Silver medalist of International Genetic Engineered Machine Contest 2015
  • Silver medalist of International Genetic Engineered Machine Contest 2014
  • Corresponding author of Jian, Haoran Honor Scholar Rewards 2010
  • Corresponding author of Jian, Haoran Honor Scholar Rewards 2012
  • Corresponding author of Jian, Haoran Honor Scholar Rewards 2014
  • Guided undergraduates finish national innovation project and got "Challenge prize in Gansu province" in 2012
  • Outstanding guided teacher of undergraduate Innovation project

 

社会工作

2014年-Journal of Applied Environmental Microbiology 杂志编委。
2013年-国际生物技术与食品科学杂志主编 (International Journal of Biotechnology and Food Sciences, Editor-in-Chief)
2011年- 中国微生物学会环境微生物专业委员会委员
2010年- 担任多家杂志的资深审稿人,包括AEM,JB,JHM,IBB,Ecotoxicology等
2011年-担任兰州大学萃英学院生物学拔尖班2010级学业导师,该班15名学员均获得国内外著名高校、研究机构的保送研究生、博士生资格

Year 2014 till now: Editorial board member of Journal of Applied Environmental Microbiology

Year 2013 till now: Editor-in-Chief of International Journal of Biotechnology and Food Sciences

Year 2011 till now: Professional committee of environmental microorganism of Chinese Microbiology Society

Year 2010 till now: senior reviewer of various journal including AEM, JB, IBB, Ecotoxicology and so on

Year 2011 till now: academic supervior of grade 2010 biology top-class of cuiying college in Lanzhou University. 15 members got the qualification to further study in famous universities and academic institute at home and aboard

其它信息

实验室成员去向:

2013级本科生:一人赴美国克莱姆森大学攻读博士学位并获博士全额奖学金
2014级硕士生:武奇(wuq_10@lzu.edu.cn)至南京圣和药业股份有限公司从事科研工作
2012级博士生:陈正军(chenzhengjun85@126.com)至甘肃农业大学生命科学技术学院任教,职称:副教授
2013级硕士生:吴文扬(wuwy09@lzu.edu.cn)获国家留学基金委资助赴阿姆斯特丹大学(UvA)攻读博士学位
2013级硕士生:巫可佳(wukj13@lzu.edu.cn)在新东方教育集团担任高中培训教师
2014级博士生:李雅博(liyb11@lzu.edu.cn)2015年获国家留学基金委资助赴美国哈弗医学院(HMS)交流两年
2014级博士生:于政升(yuzs11@lzu.edu.cn)2015年获国家留学基金委资助赴俄克拉荷马大学(OU)交流一年
2012级硕士生:陶玄宇(taoxuanyu@126.com)获美国俄克拉荷马大学(OU)博士全额奖学金
2012级硕士生:黄海鹰(huanghy89@126.com)获国家留学基金委资助赴德国慕尼黑工业大学(TUM)攻读博士学位
2012级硕士生:姜一鸣(jiangym89@126.com)获国家留学基金委资助赴德国亥姆霍兹联合会环境与健康研究中心(HUMG, Munich)攻读博士学位
2012级硕士生:郑喆(zhengzhe0826@163.com)至兰州生物制品所从事科研工作
2011级硕士生:张笑薇(smile19880726@gmail.com)获香港大学博士全额奖学金
2011级硕士生:邹路明(lumingzou@gmail.com)中科院遗传所攻读博士
2010级本科生:一人保送至清华大学、一人保送至中科院微生物所、两人赴美国俄克拉亥玛大学完成本科毕业论文并获博士全额奖学金
2009级本科生:一人获香港大学全额奖学金、一人保送至清华大学医学院、一人保送至北京大学
2008级本科生:一人保送至北京大学、一人保送至复旦大学

 

 

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