兰州大学生命科学学院 教授、博导 邱全胜 (Dr. Quan-Sheng Qiu)

学习经历

1981-1985    学士, 兰州大学生物系植物生理专业

1985-1988    硕士, 兰州大学生物系植物生理专业

1991-1994    博士, 兰州大学生物系植物生理专业

1994-1996    博士后, 中科院生物物理所生物大分子国家重点实验室

2000-2009    博士后,University of Illinois,University of Arizona等
 

工作经历

2009-现在    教授, 博士生导师, 兰州大学萃英特聘教授, 兰州大学生命学院

1996-2000    副教授, 北京师范大学生命学院

1988-1994    助教, 讲师, 兰州大学生物系
 

教学及指导研究生情况

讲授本科生专题课《植物蛋白组学概论

讲授研究生课程《植物蛋白组学研究进展》

实验室现有博士研究生3名:樊立刚,潘婷,张肖。

实验室现有硕士研究生9名:朱小杰,苏小梦,李晓娇,龚稻稻,赵映甲,王秀芳,李战超,吕莎莎,陈亚珠。

发表论文及专著

1.      Fan L, Zhao L, Hu W, Li W, Novak O, Strnad M, Simon S, Friml J, Shen J, Jiang L, Qiu QS. Na+,K+/H+ antiporters regulate the pH of endoplasmic reticulum and auxin‐mediated development. Plant Cell Environ. 2018, 41: 850-864

2.      Pan T, Liu Y, Su X, An L, Qiu QS. Domain-switch analysis of PeNHX3 from Populus euphratica reveals the critical role of the transmembrane domain 11 in Na+ and Li+ transport. Journal of Plant Physiology, 2017, 219: 1-11

3.      潘婷,邱全胜. N-端结构域决定拟南芥KEA1和KEA2的亚细胞定位及功能. 中国科技论文, 2017, 12 (18): 2124-2129

4.      邱全胜. 拟南芥NHX5和NHX6:离子平衡与蛋白质运输. 中国科学: 生命科学, 2017, 47: 839–846

5.      邱全胜. 植物液胞观察,分离纯化及H+-ATPase活力测定. 细胞生物学实验,第4版. 实验八. 高等教育出版社, 北京. 2017,60-64页。

6.      Qiu QS. AtNHX5 and AtNHX6: Roles in protein transport. Plant Signal Behav., 2016, 11(6): e1184810.

7.      Qiu QS. Plant endosomal NHX antiporters: activity and Function. Plant Signaling & Behavior, 2016, 11(5):e1147643

8.      Wu X, Ebine K, Ueda T, Qiu QS. AtNHX5 and AtNHX6 Are Required for the Subcellular Localization of the SNARE Complex That Mediates the Trafficking of Seed Storage Proteins in Arabidopsis. PLoS ONE, 2016, 11(3): e0151658.

9.      Wang L, Wu X, Liu Y, Qiu QS. AtNHX5 and AtNHX6 Control Cellular K+ and pH Homeostasis in Arabidopsis: Three Conserved Acidic Residues Are Essential for K+ Transport. PLoS ONE, 2015, 10(12): e0144716.

10.   Wang L, Feng X, Zhao H, Wang L, An L, Qiu QS. Functional Analysis of the Na+,K+/H+ Antiporter PeNHX3 from the Tree Halophyte Populus euphratica in Yeast by Model- Guided Mutagenesis. PLoS ONE, 2014, 9(8): e104147.

11.   Zheng S, Pan T, Fan L, Qiu QS. A Novel AtKEA Gene Family, Homolog of Bacterial K+/H+ Antiporters, Plays Potential Roles in K+ Homeostasis and Osmotic Adjustment in Arabidopsis. PLoS ONE, 2013, 8(11): e81463.

12.   Zhang Z, Zhang Q, Wu J, Zheng X, Zheng S, Sun X, Qiu QS*, Lu T. Gene knockout study reveals that cytosolic ascorbate peroxidase 2(OsAPX2) plays a critical role in growth and reproduction in rice under drought, salt and cold stresses. PLoS ONE, 2013, 8(2): e57472. (*Co-corresponding author)

13.   Qiu QS. V-ATPase, ScNhx1p and yeast vacuole fusion. JGG, 2012, 39: 167-171

14.   Qiu QS. Plant and yeast NHX antiporters: roles in membrane trafficking. J Integr Plant Biol, 2012, 54: 66–72

15.   Sasser T, Qiu QS*, Karunakaran S, Padolina M, Reyes A, Flood B, Smith S, Gonzales C, Fratti RA.The yeast lipin 1 orthologue Pah1p regulates vacuole homeostasis and membrane fusion. J Biol Chem, 2012, 287: 2221–2236 (*Co-first author)

16.   Qiu QS, Fratti RA. The Na+/H+ exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion. J Cell Sci, 2010, 123: 3266.

17.   Qiu QS, Huber JL, Booker FL, Jain V, Leakey A, Fiscus EL, Yau PM, Ort DR, Huber SC. Increased protein carbonylation in leaves of Arabidopsis and soybean in response to elevated [CO2] and [O3]. Photosyn Res, 2008, 97:155-66 

18.   Qiu QS, Hardin SC, Brutnell TP, Huber SC. Light and metabolic signals control the selective degradation of SUS in maize leaves during de-etiolation. Plant Physiol, 2007, 144: 468-478

19.   Fuglsang AT, Guo Y, Cuin TA, Qiu QS, Song C, Kristiansen KA, Bych K, Schulz A, Shabala S, Schumaker KS, Palmgren MG, Zhu JK. Protein kinase PKS5 inhibits the plasma membrane H+-ATPase by preventing interaction with 14-3-3 protein. Plant Cell, 2007, 19:1617-34  

20.   Batelli G, Verslues PE, Agius F, Qiu QS, Fujii H, Pan S, Schumaker KS, Grillo S, Zhu JK. SOS2 promotes salt tolerance in part by interacting with the vacuolar H+-ATPase and upregulating its transport activity. Mol. Cell. Biol. 2007, 27:7781-90 

21.   Qiu QS, Guo Y, Quintero FJ, Pardo JM, Schumaker KS, Zhu JK. Regulation of Vacuolar Na+/H+ Exchange in Arabidopsis thaliana by the Salt-Overly-Sensitive (SOS) Pathway. J Biol Chem, 2004, 279: 207.

22.   Guo Y, Qiu QS, Quintero FJ, Pardo JM, Ohta M, Zhang C, Schumaker KS, Zhu JK. Transgenic Evaluation of Activated Mutant Alleles of SOS2 Reveals a Critical Requirement for Its Kinase Activity and C-Terminal Regulatory Domain for Salt Tolerance in Arabidopsis thaliana. Plant Cell, 2004, 16:435.

23.   Song CP, Guo Y, Qiu QS, Lambert G, Galbraith DW, Jagendorf A, Zhu JK. A probable Na+(K+)/H+ exchanger on the chloroplast envelope functions in pH homeostasis and chloroplast development in Arabidopsis thaliana. Proc Natl Acad Sci U S A, 2004, 101: 10211.

24.   Qiu QS, Vera-Estrella R, Barkla BJ, Zhu JK, Schumaker KS. Na+/H+ exchange activity in the plasma membrane of Arabidopsis thaliana. Plant Physiol, 2003,132: 1041.

25.   Qiu QS, Guo Y, Dietrich MA, Schumaker KS, Zhu JK. Regulation of SOS1, a plasma membrane Na+/H+ exchanger in Arabidopsis thaliana, by SOS2 and SOS3. Proc Natl Acad Sci U S A, 2002, 99: 8436.

26.   Qiu QS, Zhang N. Water stress inhibited PNPP hydrolysis activity of the plasma membrane H+-ATPase from soybean hypocotyls. Australian J. Plant Physiol., 2000,27: 717

27.   Qiu QS,Wang ZZ, Zhang N, Cai QG, Jiang RX. Aquaporins at the leaf callus protoplasts from Actinidia deliciosa var deliciosa cv. Hayward. Australian J. Plant Physiol., 2000,27:71

28.   Qiu QS. Characterization of PNPP hydrolysis by plasma membrane H+-ATPases from soybean hypocotyls. J. Plant Physiol, 1999,154:628

29.   Qiu QS, Su XF. The influence of extracellular side Ca2+ on the activity of the plasma membrane H+-ATPase from wheat roots. Australian J. Plant Physiol. 1998, 25(8):923

30.   Qiu QS, Cheng P, Liang HG. Characterization of the NAD(P)H oxidation by purified plasma membrane vesicles using a spin-trapping EPR method. J. Plant Physiol. 1995,146: 445

31.   Qiu QS, Liang HG. Lipid peroxidation caused by the redox system of plasma membranes from wheat roots. J. Plant Physiol. 1995, 145: 261

32.   Qiu QS, Liang HG, Zheng HJ, Cheng P. Ca2+-calmodulin-stimulated superoxide generation by purified plasma membrane from wheat roots. Plant Science, 1994,101: 99

33.   Qiu QS, Wang ZZ, Cai QG, Jiang RX. The changes of DHN1 expression and subcellular distribution in A. delicisoa cells under osmotic stress. Sci in China, 2002, 45: 1

34.   Cheng XY, Zheng HJ, Yang CD, Qiu QS, Wang Q, Pang HM. The changes of calmodulin level and its relations with the flowering and senescence in Lemna perpusillal 6746. Chinese Sci. Bullet. 1992, 37: 1653

研究方向

我们课题组主要研究植物Na+,K+/H+反向转运蛋白在植物生长发育中的功能。Na+,K+/H+反向转运蛋白的生化活力是跨膜转运Na+或K+,同时反向交换质子(H+)。因此,Na+,K+/H+反向转运蛋白在维持细胞离子和pH稳态平衡方面起着重要作用。拟南芥基因组含有大量的Na+,K+/H+反向转运蛋白,可以分为三个亚家族,即NHXs,CHXs和KEAs。我们以拟南芥和酵母作为模型生物系统,重点研究NHX和KEA基因家族的离子转运活性和生理功能。我们的研究目标是揭示NHX和KEA在Na+和K+转运,pH平衡,膜微囊运输,耐盐胁迫以及植物生长发育等过程中的生物功能。

Our group is interested in exploring the role of Na+,K+/H+ antiporters in plants. The biochemical function of the Na+,K+/H+ antiporter is to transfer the Na+ or K+ across a membrane in exchange for protons (H+). The Na+,K+/H+ antiporter thus is crucial for cellular ion and pH homeostasis. The Arabidopsis genome has a large Na+,K+/H+ antiporter family that contains three subfamilies: NHXs, CHXs and KEAs. Using Arabidopsis and yeast as model systems, we are focusing on characterizing the ion transport activity and physiological function of the NHX and KEA gene families. We aim to investigate their roles in Na+ and K+ transport, pH homeostasis, membrane trafficking, salt tolerance, and the regulation of growth and development.

项目成果
荣誉、获奖
社会工作

2017-present      Journal of Plant Physiology, Editor-in-Chief

2015-现在   《植物学报编委

2012-现在   《西北植物学报编委

其它信息
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