- Bio
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1986年8月至1991年1月,在甘肃农业大学基础部,任助教,讲师。
1991年至今,在兰州大学生命科学学院,任副教授。
2012年至今,任教授,博士生导师。
- Academic Appointments
- Honors & Awards
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甘肃省第十届高校青年教师成才基金,2004年10月
兰州大学首届“隆基教育教学奖”,2007年12月
兰州大学第二届 “教学新秀一等奖”,2000年12月
2010年获得甘肃省科技进步二等奖(3/6)2010年10月
2013年获得兰州大学教学成果一等奖(2/5),2013年9月
2014年获得甘肃省教学成果二等奖(2/5),2014年4月
- Funding
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近年来承担的科研项目:
1. Pax6基因和Pax6基因突变体在非洲爪蟾眼睛发育过程中的相互作用及分子机制 (批准号:31471953),国家自然科学基金面上项目,项目起止年月:2015年01月至 2018年12月,项目负责人
2. 紫外辐射引起角膜上皮细胞凋亡的分子机理研究(批准号:30970312).国家自然科学基金面上项目,项目负责人
3. 无尾两栖类蝌蚪晶状体再生的分子机理研究(批准号:30570224).国家自然科学基金面上项目,项目负责人
4. 冷水性鱼优良新品种的引进及新技术试验示范推广(批准号:20090478). 甘肃省星火计划项目,项目负责人
5.国家林业局玛曲湿地生态保护示范工程项目. 国家林业局湿地项目,项目负责人。
6. 黄河首曲自然保护区生物多样性调查(批准号:20101209-364),甘肃省甘南藏族自治州,项目负责人。
7.无尾两栖类晶状体再生相关基因的分析测定,甘肃省自然科学基金(批准号:3ZS061-A25-060),项目负责人。
8.甘肃黄河首曲湿地黑颈鹤的种群数量动态和食性分析,中国野生动物保护协会,项目负责人。
9.教学标本标准化整理整合及共享,(批准号:2005DKA21403),科技部十一五重大专项,主要参加人。
10.青藏高原社区天然草地保护与合理利用技术研究与示范,国家农业部公益性行业(农业)科研专项(批准号:201203006)。
11.紫外辐射引起无尾两栖类角膜上皮细胞凋亡的分子机理研究,甘肃省自然科学基金(批准号:2011GS04080),项目负责人。
12.氧化石墨烯的小鼠眼毒性评估,甘肃省自然科学基金(批准号:17JR5RA220),2017年9月至2019年9月,项目负责人。
- Publications
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近期研究论文:
Yongpeng Shi, Hui Cai, Zhanyu Niu, Jiande Li, Gaowei Pan, Huanbing Tian, Li Wei, Linchi Chen, Pengfei Yang, Ji Wang, Hanwen Cao, Lan Gao* Acute oral colchicine caused gastric mucosal injury and disturbance of associated microbiota in mice. Toxicology (2021),Volume 461.
Zhanyu Niu, Yongpeng Shi, Jiande Li, Shufan Qiao, Shaobo Du, Linchi Chen, Huanbing Tian, Li Wei, Hanwen Cao, Ji Wang, Lan Gao* Protective effect of rapamycin in models of retinal degeneration. Experimental Eye Research (2021),Volume 210.
Jiande Li , Shaobo Du , Yongpeng Shi , Jiangyuan Han , Zhanyu Niu , Li Wei , Pengfei Yang , Linchi Chen , Huanbing Tian , Lan Gao*, Rapamycin ameliorates corneal injury after alkali burn through methylation modification in mouse TSC1 and mTOR genes. Experimental Eye Research 203 (2021) 108-399
Yongpeng Shi, Jiande Li, Pengfei Yang, Zhanyu Niu, Li Wei, Linchi Chen, Lan Gao* Colchicine increases intestinal permeability, suppresses inflammatory responses,and alters gut microbiota in mice Toxicology Letters (2020),Volume 334, 1 November 2020, Pages 66-77Shaobo Du, Jiande Li, Linchi Chen, Zhanyu Niu, Lan Gao*. Dynamic changes in and time sequence of ultraviolet B-induced apoptosis in rat corneal epithelial cells. Arquivos Brasileiros de Oftalmologia.(2020) (Accepted; vol:ABO 85, iss:3).
Wenzhen Ana, Ying Zhanga, Xuan Zhanga, Kang Lia, Yujun Kangb, Shahnaz Akhtara, Xueli Shaa, Lan Gao* "Ocular toxicity of reduced graphene oxide or graphene oxide exposure in mouse eyes" Experimental Eye Research 174 (2018) 59–69
Shahnaz Akhtar, Wenzhen An, Xiaoying Niu, Kang Li, Shahzad Anwar, Khan Maaz, Muhammad Maqbool, Lan Gao* “Toxicity of PEG-Coated CoFe2O4 Nanoparticles with Treatment Effect of Curcumin” Nanoscale Research Letters 13 (2018) 52.
Shaobo Du, Biao Han, Kang Li, Xuan Zhang, Xueli Sha, and Lan Gao* Lycium barbarum Polysaccharides Protect Rat Corneal Epithelial Cells against Ultraviolet B-Induced
Apoptosis by Attenuating the Mitochondrial Pathway and Inhibiting JNK Phosphorylation, BioMed Research International, Volume 2017 (2017), p. 5806832
Wenzhen An, Biao Han, Kang Li, Shahnaz Akhtar, Ying Zhang, Xuan Zhang, Xueli Sha, Lan Gao* The protective study about alleviation of simvastatin on the damages of
PEG-BNs in mice, Environmental Toxicology and Pharmacology 53C (2017) pp. 64-73.Ju, Furong; Zhao, Yongqing; Zhao, Yuanlin; Wang, Ying; Wen, Fan; Ye, Lin; Lan Gao*, Interaction between Pax6 and its novel mutant in Bufo raddei Strauch, MOLECULAR VISION, 17(292), pp 2698-2705, 2011/10/18.
Zhao, Yongqing; Ju, Furong; Zhao, Yuanlin; Wang, Lei; Sun, Zhenglong; Liu, Mingxin; Lan Gao*, The expression of alpha A- and beta B1-crystallin during normal development and regeneration, and proteomic
analysis for the regenerating lens in Xenopus laevis, MOLECULAR VISION, 17(87), pp 768-778, 2011/3/23.
Xu, Hua; Gao Lan; Che, Tuanjie; Du, Wenjing; Li, Qiang; Gao, Qingxiang; *Wang, Ziren, The Effects of C-12(6+) Irradiation on Cell Cycle, Apoptosis, and Expression of Caspase-3 in the Human Lung Cancer Cell
Line H1299, Cancer Biotherapy and Radiopharmaceuticals, 27(2), pp 113-118, 2012/3.
Liu Yong; Wang Rong; Gao Lan; Jia Zhengping; Xie Hua; Zhang Junli; Ma Jun; Zhang Aimei; Xie Xihui, Capillary Electrophoresis Detection of Lung Cancer and Adjacent Normal Tissue Differences in Protein Mixture,
ACTA CHIMICA SINICA, 69(5), pp 543-547, 2011/3/14.
Gao, Lan.; Sun, Y.; Chen, C.; Xi, Y.; Wang, J.; Wang, Z., Primary mechanism of apoptosis induction in a leukemia cell line by fraction FA-2-b-ss prepared from the mushroom Agaricus blazei Murill,
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 40(11), pp 1545-1555, 2007/11.
Liu Yong; Wang Rong; Gao Lan; Jia Zheng-Ping; Xin Xiao-Ting; Xie Hua; Ma Jun, Methodology Research on P53 Gene Mutation Detection Exon 7 of Lung Cancer by Capillary Electrophoresis with
Single Strand Conformation Polymorphism and Restriction Fragment Length Polymorphism, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 37(10), pp 1494-1498, 2009/10.
Jianlin Wang,Gao Lan,Cui-Sheng,Gen-Xuan Wang and Hai-Yan Li:The arterial supply of the cubital joint in the bactrian camel. The Veterinary Research Communications, 2000,24(1):1-9.
Jianlin Wang,Gao Lan,Gen-Xuan Wang and Hai-Yan Li: The arterial supply to the digits of the forelimb in the Bactrian camel (Camelus bactrianus), Journal of Anatomy, 2000,196(2): 193-202.
Jianlin Wang,Gao Lan,Cui-Sheng, Gen-Xuan Wang and Hai-Yan Li: Anatomical subdivisions of the stomach of the bactrian camel (Camelus bactrianus). Journal of Morphology, 2000,245(2):161-167.
Blair, Christopher; Davy, Christina M.; Ngo, Andre; Orlov, Nikolai L.; Shi, Hai-tao; Lu, Shun-qing;Gao Lan; Rao, Ding-qi; Murphy, Robert W. Genealogy and Demographic History of a Widespread
Amphibian throughout Indochina JOURNAL OF HEREDITY, 104(1), pp 72-85, 2013/2 JAN-FEB.
教材、著作、译著
1. 生物学综合野外实习指导(冯虎元,高岚主编),2011年6月出版,高等教育出版社 (书号:978-7-04-032700-7,35万字)
2. 动物生物学实验指导(双语),2003出版,兰州大学出版社,3/3.
3. 甘肃黄河首曲省级自然保护区综合科学考察报告(主编),2011年.